How Are Proteins Categorized?

Proteins are categorized into groups called “protein families” based on shared evolutionary origins and similar characteristics.

 

Families: Superfamilies

Proteins in superfamilies are more distantly related to one another.

Example: myoglobin and hemoglobin to neuroglobin

Proteins classified by their shape are either globular or fibrous.

Globular Proteins

Globular proteins (aka spheroproteins) are spherically shaped. 

Examples: hemoglobin, immunoglobulins

Soluble in: water, acids, bases

Fibrous proteins

Fibrous proteins (aka scleroproteins) are elongated and strandlike, like wires.

Examples: keratin, collagen, elastin

Soluble in: strong acids and alkalis

Insoluble in: water, weak acids, weak bases

Proteins classified by composition are either simple or conjugated.

Simple Proteins

Simple proteins contain only amino acids.

Conjugated Proteins

Simple proteins contain only amino acids.

Conjugated proteins contain both a protein and a non-protein component.